Pycnogenol 50mg Capsule 10pcs

How does Proanthocyanidin work?

Proanthocyanidin is a polyphenolic compound that is extracted from grape seeds. It is an antioxidant with anti-inflammatory and vasodilating properties. It helps to dilate the constricted blood veins to reduce the tension on the blood vessels to restore normal blood flow. This is how it works to treat the symptoms of varicose veins such as itching, heaviness, swelling, and pain.

Composition

Each capsule contains Proanthocyanidins 50 mg extracted from French maritime pine bark, standardized to 65% to 75% of procyanidins.

Benefits:

• Pycnogenol is used to slow the aging process and maintain healthy skin, eyes, and joint tissues
• It supports a healthy and balanced immune system response to normal metabolic stress
• It acts as a potent natural scavenger of free radicals and protects the body's tissues from oxidative stress
• It can support healthy cardiovascular function by reducing triglycerides and maintaining cholesterol levels in the body

Quick Suggestions:

• Proanthocyanidin is prescribed to reduce swelling and restore normal vein function in patients with varicose veins.
• Do not take it for more than three months without medical supervision.
• Inform your doctor if you are pregnant or breastfeeding.
• Try to keep regular appointments with your doctor. This is so your doctor can check on your progress.

Pharmacology

French maritime pine bark extract is made by extraction of the outer bark of Pinus pinaster. Recent research suggests significant antioxidant activity is primarily based on its proanthocyanidin content. Proanthocyanidins prevent the oxidation of LDL cholesterol, protect the DNA from free-radical damage, prevent stress-related blood clotting without increasing bleeding risk, increase nitric oxide synthesis leading to vasodilation, have profound anti-inflammatory activity, protect the skin from sun damage, dramatically improve wound healing while decreasing scarring, boosts many aspects of immune system function, and also lowers blood sugar while stimulating fat tissue breakdown.

Dosage & Administration

Generally, one capsule (50 mg) 2 times daily with meals for 2-3 months or as directed by the physician. A repeated course or long-term use is acceptable. 

• Hypertension, blood hyper-coagulation, impaired circulation: 50 mg twice daily
• Diabetes: 50 mg twice daily
• Retinopathy: 50 mg twice or thrice daily
• Asthma: 1 mg/lb of body weight/day in two divided doses or 50 mg twice daily
• Allergies: 50 mg twice daily
• As an anti-inflammatory agent: 50 mg once or twice daily
• Osteoarthritis: 50 mg twice daily
• Dysmenorrhea/Endometriosis: 50 mg once or twice daily
• Skin disorders/Melasma: 50 mg once or twice daily
• Edema in venous insufficiency: 50 mg once daily minimum 2-4 weeks (For more advanced stages the daily dosage should be higher, 50 mg twice or thrice daily for 4 weeks). Once edema and symptoms have improved, a daily maintenance dosage of 50 mg may be considered.
• As an antioxidant: 50 mg once daily

Interaction

There is no reported information on drug interaction resulting from simultaneous intake of Pycnogenol with other drugs.

Contraindications

There are no known contraindications for Proanthocyanidins.

Side Effects

No serious side effects have been reported. To avoid gastric upset, diarrhea & constipation, Pycnogenol should be taken with meals. Minor adverse effects including headache and dizziness may occur.

Pregnancy & Lactation

As a general precaution, pregnant women should not take Proanthocyanidins within the first 3 months of pregnancy. Safety trials have demonstrated an absence of mutagenic and teratogenic effects, no perinatal toxicity, and no negative effects on fertility. There are no adequate and well-controlled studies of Proanthocyanidins in children under the age of 6 years.

Storage Conditions

Store in a cool and dry place, and protect from light. Do not use the drug after the expiry date. Keep out of reach of children.